Just another day on the boards.......... Anyway, some good info got posted, but to answer your Q; yes, you can size wire by distance between components whether they're XO parts on a board or amp, speakers, etc..
Back when I started designing electrical distribution gear, we often had to provide [multiple] huge, hard wired solenoid relay panels to turn off/on/sequence up to hundreds of motors in a plant or in just one section of it if automotive or similar, so the amount of high quality stranded wire required demanded that we size wire based on load, not what the entire panel [or section of] load was, so while it might start out at 8 ga it could be 24 ga at the return point.
I don't recall checking how much we typically used on those, but one year saw an end-of-year Southwire invoice for 10 mil ft. of 14 ga [our standard control wiring] and we were a relatively tiny plant by assembly plant standards.
GM






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